Senna Extract Manufacturers in India
Available from 1% to 30% sennosides, in USP and ethanol grades, as free-flowing powder or granules.
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Ingex Botanicals is a vertically integrated senna extract manufacturer and supplier producing Sennagex®, a Cassia angustifolia leaf extract standardised to sennosides A and B. Manufactured at our NSF GMP–certified facility near Bangalore using green ethanol extraction — never methanol — Sennagex® is supplied in bulk to pharmaceutical, nutraceutical, herbal tea and animal health manufacturers across North America, Europe, the Middle East and Asia.
What is Sennagex®?
Sennagex® is a standardised extract of Cassia angustifolia Vahl (Tinnevelly senna) leaf, produced by Ingex Botanicals as a bulk ingredient for digestive-health and cleanse formulations.
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The extract is standardised to sennosides, dianthrone glycosides of which sennoside A and sennoside B are the principal actives. These compounds pass through the upper intestinal tract largely unabsorbed and are converted by colonic microflora into rhein-anthrone, the metabolite responsible for senna's recognised effect on colonic motility.
Sennosides C and D, rhein-8-glucoside and tinnevellin glycoside are present as characteristic minor constituents.
As a raw material supplier, Ingex Botanicals supplies Sennagex® to specification. Finished-product claims, dosage and labelling remain the responsibility of the formulator under the regulations of the destination market.
Our Regulatories
UV or HPLC: Choosing Your Standardisation Method
UV-Vis Spectrophotometric
The method described in most pharmacopoeial monographs for senna. It measures total sennosides as a single value after alkaline hydrolysis. Specify UV when your finished product must comply with a pharmacopoeial senna monograph.
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HPLC
Resolves and quantifies sennoside A and sennoside B individually. Because it excludes structurally related compounds that contribute to a UV reading, an HPLC value is typically lower than a UV value on the same material. Specify HPLC for marker-level control, tighter batch reproducibility, or compound-specific regulatory data.
Practical note for buyers. A quotation for "20% sennosides" means very different things by UV and by HPLC. Always confirm the method before comparing supplier prices. Ingex Botanicals states the analytical method on every Certificate of Analysis.
Discover Senna (Cassia angustifolia)
Cassia angustifolia, commonly known as Senna, is a valuable plant in both Ayurveda and modern medicine. It is widely used for treating constipation, purifying the blood, and enhancing skin health.
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Historical and Medicinal Significance
Senna, native to tropical Africa, was introduced to Tamil Nadu, India, in the 11th century. Its medicinal use dates back to the 9th century A.D., when Arabian physicians first utilized it. Traditionally, it has been used in Arabic and European medicine primarily as a cathartic. Senna leaves, when brewed into tea, are known for their strong laxative effect.
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Versatile Benefits of Senna Extract
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Laxative and Health Benefits
According to historical texts, including those by Ibn Al-Qayyim, Senna is not only a laxative but also relaxes muscles, improves hair texture, and helps against lice, headaches, rashes, and epilepsy. Unlike Henna, Senna can be applied to hair without coloring it, making it thicker, glossier, and healthier.
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Active Compounds in Senna
Senna leaves contain anthraquinone derivatives, including dianthrone glycosides (1.5% to 3%) and the crystalline glucosides sennoside A and B. These compounds, extracted from leaves and immature pods, offer purgative, antimicrobial, anticancer, and antioxidant properties. The primary laxative effect of Senna is due to sennosides A and B.
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Therapeutic Properties
Sennosides A and B, which are stereoisomers of dihydrodianthraone glucosides, contribute over 80% of Senna's biological activity. The extract has antibacterial, antifungal, anti-inflammatory, and antispasmodic properties, and can inhibit or destroy viruses. Phytochemicals in Senna also stimulate cellular regeneration, and aid in detoxifying and cleansing the body.
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Traditional and Modern Usage
Senna Extract is the most widely used anthranoid drug today, employed for centuries in both Western and Eastern medicine systems as a laxative. It is typically consumed as a tea or in powdered form. Various traditional medicine systems, including Unani, Ayurvedic, Homeopathic, and Allopathic medicines, recognize its benefits.
Frequently asked questions
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